Subject description - BEAM31NPG

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BEAM31NPG Neurophysiology
Roles:PV, PS Extent of teaching:2P+2C
Department:13131 Language of teaching:EN
Guarantors:  Completion:Z,ZK
Lecturers:  Credits:6
Tutors:  Semester:Z


The course will provide an introduction to the structure and function of the neural system and the mechanisms behind major diseases of the human brain. It will combine topics from various disciplines ranging from electrophysiology, neurobiology, neuroanatomy, neurology, psychiatry to biophysics and bioengineering. Understanding the principles how the human brain works in health and disease represents a crucial prerequisite for the development and implementation of modern engineering technologies to better diagnose and treat brain disorders.

Course outlines:

1. General neurophysiology. The neuron and the glial cell. Basic functions of synapses. Review of neurotransmitters and neuromodulators. Mechanisms of synaptic transmission.
2. Electrophysiology of the neuron. The resting membrane potential: Ionic and electric gradients. Action potentials: Properties of excitable membranes. Postsynaptic potentials, excitation, and inhibition. Generator potentials in receptors. Recording and stimulation of neural cells.
3. Electrical properties of a volume conductor, extracellular recording, and stimulation. EEG, event-related potentials.
4. Reflex and non?reflex activity. Learning and memory.
5. Functions of the spinal cord. Physiology of the brain stem: the medulla, the pons, the mesencephalon. Hypothalamus and the autonomic nervous system.
6. Motor functions: The cerebral cortex, the basal ganglia, and the cerebellum. Pyramidal and extrapyramidal systems. Demyelinization. Disorders of motor functions
7. Functions of the thalamus and physiology of pain. Somatosensory system.
8. The cerebral cortex and intellectual brain functions. Motivations and emotions.
9. Sleep and wakefulness, modulatory systems of the brain.
10. Neurophysiology of vision and hearing. The chemical senses of taste and hearing
11. Consciousness and its disorders
12. Brain metabolism and circulation. Stroke.
13. Epilepsy and seizures.
14. Degenerative diseases of the brain. Schizophrenia and mood disorders.

Exercises outline:


1. Guyton and Hall Textbook of Medical Physiology
2. Neuroscience: Exploring the Brain. M. Bear, B.W.Connors, M.A. Paradiso


Subject is included into these academic programs:

Program Branch Role Recommended semester
MEBIO4_2018 Signal Processing PS 1
MEBIO3_2018 Image Processing PV 1
MEBIO2_2018 Medical Instrumentation PS 1
MEBIO1_2018 Bioinformatics PV 1

Page updated 23.4.2024 17:51:08, semester: Z/2024-5, Z,L/2023-4, Send comments about the content to the Administrators of the Academic Programs Proposal and Realization: I. Halaška (K336), J. Novák (K336)