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Explanatory Notes
Instructions
Anotation:
This course introduces the physical, electronic, biological principles of biosensors and provides information on past, present and future technologies. Various mechanisms and sensor concepts for specific applications (such as detection of glucose, urea, proteins, cells, bacteria, etc.) are explained. In addition, the course introduces the use of modern nanostructures and nanomaterials in biosensors to achieve reliable and sensitive devices for diagnosis at the point of care, in food safety or environmental monitoring. We will also discuss current challenges and future perspectives for various applications of biosensors.
Course outlines:
| 1. | | Overview of biosensors - Introduction and concept of biosensor |
| 2. | | Biosensor development - ideal biosensor characteristics |
| 3. | | Bioreceptor - catalytic (equilibrium) and affinity (equilibrium) |
| 4. | | Surface Function - Physical and Chemical Immobilization |
| 5. | | Electrochemical and Electrochemiluminescence - Overview and Applications |
| 6. | | Optical - fluorescence and colorimetric study |
| 7. | | Field controlled transistors - Sensors and applications |
| 8. | | Nanobiosectors - top down (nanostructures) |
| 9. | | Nanobiosectors - bottom up (nanomaterials) |
| 10. | | BioMEMS / NEMS - Microfluidic, SAW |
| 11. | | Application of biosensors - market for health care |
| 12. | | Reliability of biosensors - in food and environment |
| 13. | | New trends in biosensors - wearable biosensors, laboratory on chip |
| 14. | | Current global biosensors challenges and future developments, final summary |
Exercises outline:
The laboratory exercises introduce the construction and functional principles of biosensors in a practical and entertaining way. Exercises take place in the form of independent work of students in the laboratory and demonstrations.The exercises also include an excursion to collaborating research institutes.
Literature:
| [1] | | New Perspectives in Biosensors Technology and Applications, Intech 2011, ISBN 978-953-307-448-1, doi:10.5772/936 |
| [2] | | Biosensors, InTech 2010, ISBN 978-953-7619-99-2, doi:10.5772/45616 |
| [3] | | Biosensors: fundamentals and applications, Oxford University Press 1989, ISBN 0198547455 |
Requirements:
Students pass the exam by written test and oral examination. Students prepare reports from laboratory exercises.
Subject is included into these academic programs:
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Proposal and Realization: I. Halaška (K336), J. Novák (K336) |